France Boehringer Ingelheim France S.A.S., Paris Labso Chimie Fine S.A.R.L., Blanquefort Great Britain Boehringer Ingelheim Ltd., Bracknell Greece Boehringer Ingelheim Ellas AE, Athens Indonesia PT Boehringer Ingelheim Indonesia, Jakarta Italy Boehringer Ingelheim Italia S.p.A., Reggello Bidachem S.p.A., Fornovo S. Giovanni Japan Nippon Boehringer Ingelheim Co. Ltd., Kawanishi Boehringer Ingelheim Shionogi Vetmedica Co. Ltd., Kawanishi Boehringer Ingelheim Seiyaku Co., Ltd., Yamagata SSP Co. Ltd., Tokyo 57 % ; Netherlands Boehringer Ingelheim B. V., Alkmaar Poland Boehringer Ingelheim Sp.zo.o., Warsaw.
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| Avodart hair regrowthN 53 ; : men 30, women 28; placebo crossover to LEV 2000 mg day n 54 ; : men 25, women 29; LEV 1000 mg day Details of pretrial period crossover to placebo n 53 ; : men 27, 12- or 8-week protocol women 26; LEV 2000 mg day crossover amendment ; baseline period. to placebo n 54 ; : men 24, women Treatment period A comprised a 30; LEV 1000 mg day crossover to LEV 4-week titration, during which LEV 2000 mg day n 53 ; : men 24, was titrated up 1000 mg day at women 29; LEV 2000 mg day crossover 2-week intervals ; until patients were to LEV 1000 mg day n 52 ; : men 27, stabilised on their assigned dose, then women 25 a 12-week evaluation. This was followed by treatment period B Age at onset of seizures crossover ; , a 4-week titration up or Onset of epilepsy: total n 324 ; : down at 1000 mg day at 2-week 13.7 years SD 11 placebo crossover to intervals ; , and 12-week evaluation LEV 1000 mg day n 53 ; : 13.1 years SD 10.5 placebo crossover to LEV ITT analysis performed method 2000 mg day n 58 ; : 15.4 years SD Authors state yes; not stated 11.2 LEV 1000 mg day crossover to placebo n 53 ; : 13.6 years SD 11.7 Sample size calculations LEV 2000 mg day crossover to placebo Sample size of 234 evaluable patients n 54 ; : 13.6 years SD 10.7 LEV was calculated to detect a reduction 1000 mg day crossover to LEV 2000 mg day in seizure frequency of 24%, n 53 ; : 12.7 years SD 11.4 LEV measured by a difference between 2000 mg day crossover to LEV 1000 mg day the log transformed treatment means n 52 ; : 13.9 years SD 11.2 ; of 0.27 two-tailed test, power 80%, 0.05, SD 0.60 ; Pretrial medication CBZ, PHT, VPA, VGB, LTG Analysis methods Primary outcome seizure frequency Ongoing concurrent medication during parallel A ; and crossover B ; All patients were taking between 1 and 3 or evaluation periods was calculated more AEDs during the study. See details of using least-squares means LSMs ; to pretrial period determine percentage reduction over placebo. Two-tailed significance tests Co-morbidities were used to assess the significance Not stated level adjusted for multiple comparisons. Continuous variables were analysed using ANOVA. Data continued.
022 DRIVING TEST SUCCESS IN STROKE PATIENTS COMPARED TO OTHER DISABLED GROUPS Hillel M. Finestone, MDCM, FRCPC ; , Medical Director of the Stroke Rehabilitation Program Shawn C. Marshall, MD, MSc, FRCPC ; , Clinical Director Acquired Brain Injury Program, lisabeth Bruyre Health Centre, The Rehabilitation Centre, Assistant Professor, University of Ottawa, Ottawa, Ontario. Richard Blair, PH.D., C.Psych, Staff Psychologist, Stroke Rehabilitation Program, lisabeth Bruyre Health Centre, Ottawa, Ontario. Lynn Hunt, MSc. OT, Director of the Driving Evaluation Program, The Rehabilitation Centre, Ottawa, Ontario. Keith O'Rourke, MBA ; Scientist, Ottawa Hospital and lisabeth Bruyre Research Institutes, Ottawa, Ontario. Objectives: The objective of this research is to determine the driving success rate of stroke patients participating in formal driving assessment compared to other disabled groups. Methods: This is a retrospective cohort study design. A total of 700 patients with stroke and other diagnoses were referred to The Rehabilitation Centre TRC ; between 1995 and 2003 to be assessed by an in-house physiatrist affiliated with the TRC Driving Assessment Program. Patient sources included former inpatients from TRC and lisabeth Bruyre Health Centre, and outpatients in the community with a noted disability. Data collected and analyzed SPSS ; included results from visual and perceptual testing Bells Test, Charrons Test, Light Board Scanner Test, Cross-checking Test, Trailmaking A & B Test ; , a Drivers Reaction Time Test, and an On-Road Driving Test. A pass or fail result was provided to each patient and the Ministry of Transportation. Results: Participants were divided into two groups for the purposes of analysis; stroke patients versus nonstroke patients. The patient population consisted of 230 stroke patients, 95 patients with traumatic brain injury, 66 patients with amputations, 44 patients with Multiple Sclerosis, 60 patients with spinal cord injury, 69 patients with neuromuscular disorders, and 136 classified as "other". The average age for stroke patients was 62 years compared with 52 years for nonstroke patients. Patients in the stroke group consisted of 78% male and 22% female group versus 71% and 29% in the nonstroke group. Preliminary statistical analysis indicates that 39% of stroke patients passed their formal driving assessment compared to 56% of all other disabled groups combined p-value 0.0001 ; . After adjustment for age and sex covariates, the pass rate differences remained statistically significant p 0.01 ; . Conclusion: A unique, large driver's database focusing on the disabled driver has been described. Stroke patients' success rates on formal driving assessment are statistically and clinically significantly different compared to other disabled groups. Visual-perceptual and other performance differences will be accounted for in future data analysis. 20 and dutasteride.
The results of the remaining parameters, contact angle, log g * and tan δ measured at 1 and 100 radians s, are presented in table 3.
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The National MS Society's Professional Resource Center Clinical Bulletin, "Pain in Multiple Sclerosis" by Heidi Malone, PhD, RN, can be downloaded at nationalmssociety PRC. It includes charts on pharmacological management and an extensive bibliography and acarbose.
In preventing strokes in clinical practice as opposed to its proven efficacy in controlled trials in patients with atrial fibrillation. Lalit Kalra, MD, PhD, FRCP Inigo Perez, MD ~ Anne Melbourn, RGN Department of Medicine Guy's, King's & St Thomas' School of Medicine London, UK.
Symbols 1 2MLTBSYR13 1CCINSUSYR13 A a botic27 ABILIFY11 ACCOLATE27 ACCUNEB3ML27 ACCUZYME17 acebutolol14 ACEON15 acetaminophenw codeine6 ACETASOLHC27 acetazolamid15 aceticacid27 ACETOHEXAMID13 acetylcyst27 aceacd alum27 ACIPHEX20 ACTHIB24 ACTIMMUNE10 ACTIQ6 ACTIVELLA21 ACTONEL21 ACTOS13 ACULAR25 ACULARLS25 ACULARPF25 acyclovir12 ADDERALLXR17 ADOXA6 adrenalin27 ADVAIRDISKU27 ADVICOR15 AEROBID27 AEROBID-M27 AEROCHAMBER27 aerootichc27 AGENERASE12 AGGRENOX14 AGRYLIN14 ak-con25 ak-poly-bac25 ak-pred25 ak-sulf25 ak-tob25 ak-trol25 AKNE-MYCIN17 ALA-CORT17 ALAMAST25 ALBENZA11 albuterol27 albuterolsulfate27 ALBUTER.5ML27 albuter3ml27 alclometasone dipropionate17 alcoholswabs13 ALCORTIN9 ALDARA24 ALINIA6 ALKERAN10 ALLEGRA27 ALLEGRA-D27 allergyrelief27 allopurinol9 ALOCRIL25 ALOMIDE25 ALORA21 ALPHAGANP25 alprostadil15 ALREX25 ALTACE15 ALTAFLUOR25 ALTOPREV15 ALUPENT27 amantadine11 AMARYL13 AMBIENPAK28 amcinonide17 AMERGE10 AMICAR14 amigesic6 amilor hctz15 amiloride15 amiloridehclw hctz15 aminocaprac14 aminophylline27 amiodarone15 amitriptylin9 amnesteem17 amox clavula6 amox kclav6 AMOXAPINE9 amoxicillin6 amoxil clavu6 amoxtr-potassium clavulanate6 amphetamine17 ampicillin6 ANABAR6 ANADROL-5021 ANALPRAM-HC17 ANAMANTLEHC25 ANCOBON9 ANDRODERM21 ANDROID21 ANEMAGENOB29 ANTABUSE19 ANTARA15 anthralin17 antiben27 antibiotear27 anucort-hc25 ANUSOL-HC25 ANZEMET9 apap codeine6 APHRODYNE21 APOKYN11 apri21 AQUACHLORAL28 aranelle21 ARANESP14 ARAVA24 argesic-sa10 ARICEPT8 ARIMIDEX23 ARISTOCORT21 ARISTOCORTHP21 ARISTOSPAN21 ARIXTRA14 ARMOURTHYRO22 AROMASIN23 ARTHROTEC5010 ARTHROTEC7510 asa codeine6 ASACOL25 ASMANEX27 ASTELINNASL27 ATACAND15 ATACANDHCT15 atenol chlor15 atenolol15 atropin-care25 atropinesul25 ATROVENT27 ATTENUVAX VACCINEW DILUENT24 AUGMENTINXR6 augbetamet17 aurodex27 auroguard27 auroto27 AVALIDE15 AVANDAMET13 AVANDIA13 AVAPRO15 AVASTIN10 AVELOX6 aviane22 AVINZA6 AVODART21 AVONEX24 and precose.
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Implementation was assigned to the appropriate vice-president. Also endorsed was the creation of a Medication Quality Improvement Committee MQIC ; , a subcommittee of the Drugs and Therapeutics Committee, whose mandate is ".to improve the prescribing, order processing, dispensing, administering and documenting steps in the medication delivery system to reduce the risk of errors." . The membership of the MQIC includes co-chairs Pat Semeniuk Professional Affairs ; and Barbara Jewesson Pharmaceutical Sciences CSU ; and representatives from the nursing, medical and pharmaceutical disciplines: Peter Dawson, PSM, Psychiatry Lori Earl, PSM, Internal Medicine Sandie Kocher, PSM, Surgery VGH ; Mary Lee Johnston, PSM, Surgery UBCH ; Leanne Heppell, PSM, Cardiology Kathy Weglo, PSC, ICU Jo-Ann Ford, CNS, GI & Solid Organ Transplant Michael Duchnych, Nurse Educator, BMT Khairrunnissa Rhemtulla, Nurse Educator, Neurosciences Jerry Chen, MD, Vascular Surgery Kenn Koo, Sterile Products Supervisor, Pharmaceutical Sciences CSU Caryn Pershick, Operations Coordinator, Pharmaceutical Sciences CSU The focus of the committee over the past year has been to facilitate the implementation of the recommendations from the external review where feasible. These include: Removal of concentrated KCl IV vials from wardstock refer to article on page 2 ; Installation of adequate lighting over the medication carts on VGH nursing units Clarification of the practice of nurses summarizing physicians' orders memo was sent to Patient Services Managers June, 2001 ; Improvement of the medication incident summary reports to facilitate a more meaningful analysis of incidents, especially those involving anticoagulants, analgesics, and insulin The MQIC will continue to review best practices in medication delivery systems and identify opportunities to reduce the risk of medication errors from occurring in our hospital. If you have any suggestions or comments in this regard, please feel free to forward these to one of the committee members and acenocoumarol.
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Novel drug discovery based on functional genomics: Another aspect of pharmacogenomics. Gozoh Tsujimoto Kyoto University, Japan.
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