I can't say I look forward to this race. It hasn't been kind to those of us who use an historic Saratoga stake race to finish off a pick three or to launch a tri or super. This is not often the place for that kind of play. There will be mysteries in this race to be sure but the solutions to the mystery are visible to anyone with past performances. This race rewards a speed profile and most of the entrants will already have churned out very fast fractions establishing their right to be in the race. Your choice here better be able to stay close to a sub 22 opening and a 45 half or you'll be looking up the track to see if you can get a third. The '04 race was an aberration, producing a winner that was five lengths off the lead early, but the winner Classic Example caught a muddy track and let a speedy front runner spread the field out chasing a 21.3 that set up her stretch run. But we were back to normal in '06; Cotton Blossom staying pinned to `modest fractions' 22.1; 45.4 ; before pulling away.
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I commend Dr Berger for his excellent letter to the editor regarding dictation in the presence of the patient. I absolutely agree with him on the importance of both the completeness and accuracy, which is enhanced, if not ensured, by dictating before distractions arise that diminish recollection of the encounter with the patient. I agree that we did not make that point directly in our article.1 We indirectly implied it on page 281 in the discussion of the "closing moments" of the medical visit, on page 282 in advising the physician to "clarify the accuracy of the medical record, " and on page 284 in stating "an extra opportunity for more information exchange, increased affiliation, and greater involvement." I thank Dr Berger for stating it more directly. John E. Sutherland, MD Waterloo, Iowa.
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As requested I have reviewed available information on the medical technologies and the market for those technologies held by Giaconda Limited Giaconda ; . I provide here an independent report for inclusion in the Prospectus issued by Giaconda dated on or about, August, 2005, for the offer of up to million Shares at a price of $AU 0.50 per Share to raise up to $AU 6 million with a minimum subscription of 12 million Shares to raise $AU 6 million. To complete this analysis I have reviewed the business strategy and the primary medical technologies and associated markets addressed by the Company. I have then considered the Companys ability to access and satisfy these markets in a reasonable time. BACKGROUND AND REVIEWER'S CREDENTIALS This report is a summary of the recent detailed technical due diligence conducted by Professor Nicholas J. Talley of Mayo Clinic and the University of Sydney for the technology portfolio of Giaconda. The summary explores the Companys research and development programs, proposed market and competition assessment for the portfolio products. Professor Talley is a Visiting Professor at the University of Sydney and Professor of Medicine at the prestigious Mayo Medical School in Minnesota, US. He also works as a Consultant in the Division of Gastroenterology and Hepatology and is Co-Director in the Centre for Enteric Neurosciences Translational and Epidemiological Research. Professor Talley has had extensive experience in both the Academic and the Commercial sectors. He is widely published, has been editor of key journals such as The American Journal of Gastroenterology and has received research awards and scholarships. In the commercial area, Professor Talley has consulted for and received support from many of the top pharmaceutical companies in the field of gastroenterology worldwide, including AstraZeneca, Novartis and Janssen. The purpose of this report is to provide information for potential investors regarding Giacondas scientific and technical resources, and thus potential to meet commercial objectives. THE SCIENCE PLATFORM Giacondas product portfolio consists of five therapeutic products indicated in the area of gastroenterology. These products comprise of novel combinations of currently registered and widely marketed drugs. The portfolio is aimed at addressing unmet medical needs in gastroenterology. The phases of development of these products are described in detail in Section 6 of this Prospectus.
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Mr. Jagjivan Ram's approach, of balance between collective bargaining and compulsory adjudication, found reflection in the Labour Relations Bill, 1950 and the Trade Unions Bill, 1950, introduced in the Parliament of India. Under the Labour Relations Bill, 1950, collective bargaining was made compulsory for both employers and unions under stipulated conditions. The Bill provided for a procedure for collective bargaining, which included the prohibition of strikes and lock-outs until the parties had resorted to collective bargaining and obligation on both the employers and workers to observe collective agreements. The government office was declared to be the purpose of collective bargaining. Mr. V.V. Giri who took over as the new Labour Minister in 1952 sought to completely overhaul the existing scheme of compulsory adjudication. At the Indian Labour Conference at Nainital, Mr. Giri tried, with moderate success to win support for shifting emphasis towards collective bargaining. Following the resignation of Mr. Giri in 1954, Mr. Khandubhai Desai took over as Labour Minister. While acknowledging that the shift from compulsory adjudication to collective bargaining was essential, he emphasized that compulsory adjudication has to be retained as a reserve weapon in the armoury of the state for tackling labour-management relations. Thus, despite attempts like the voluntary Code of Discipline in Industry adopted by the Indian Labour Conference in 1958 obliging management and unions not to take unilateral action and to settle all future disputes through conciliation, negotiation and voluntary arbitration, collective bargaining progressively took a back seat. The code of Discipline in Industry which was ratified by representatives of the All-India organizations of employers and workers in March 1958 obliging management and unions not to take unilateral action and to settle all future disputes through conciliation, negotiation and voluntary arbitration, collective bargaining progressively took a back seat. Enumerated what constituted acts of interference and declared that there has to be a just recognition by employers and workers of the rights and responsibilities of either party and that neither party will have recourse to coercion, intimidation or victimization. The Code of Discipline is a nonstatutory measure and over the Years it has lost much of its importance. Collective bargaining, which developed in the industrialized countries as the method of regulating employment relations, requires the existence of two parties, the employer and the workers. The collectives of workers ranged on one side, would in most cases, be organized into trade unions. The need for the existence of trade unions and in turn, the right of trade unions to function freely and further, the right of individual members to freely join and participate in the affairs of the trade union then would, a fortiori, be an indisputable and necessary condition for the efficient functioning of collective bargaining. Viewed in this light, any action of either party to the collective bargaining process which interferes with the formation or existence of unions or in the participation of individuals in these organizations would hamper the collective bargaining process and would merit.
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Mental Health The condition may present with insidious onset, or onset may seem sudden, with an acute psychotic break; however, prodromal symptoms are often identified retrospectively. Essential Features Presence of certain psychotic features with characteristic symptoms involving multiple psychological processes Deterioration from a previous level of functioning Onset before age 45 Duration of at least 6 months Types of Schizophrenic Disorders Schizophrenic disorders with overt psychotic features are currently differentiated into several types based on the predominant symptoms. Of these, three are most distinctive and are classically described: Disorganized type also know as hebephrenic type ; Catatonic type Paranoid type History and Physical Findings.
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Ventricular aneurysms. Clinical Reseach 1980; 28: 215A. Hecht HS, Hopkins JM, Rose JG: Location and number of diseased coronary arteries by thallium-201 myocardial imaging. Clinical Research 1980; 28: 179A. Hecht HS, Hopkins JM: Interrelationships and reproducibility of ejection fraction, maximum and average ejection velocities by radionuclide angiography. Clinical Research 1980; 28: 179A. Hecht HS, Hopkins JM, Wong M: Evaluation of hyperdynamic ejection by radionuclide angiography. Clinical Research 1980; 28: 179A. Chew CYC, Hecht HS, Schnugg SJ, Hopkins JM, Singh BN: Pacing induced decrease in radionuclide ejection fraction is a more sensitive index of myocardial ischemia than changes in transmyocardial lactate gradients. Circulation 1980; 62: Suppl III-87. Hecht HS, Chew CYC, Schnugg SJ, Hopkins JM, Singh BN: Reduction by verapamil of pacing-induced abnormalities in radionuclide ejection fraction and lactate metabolism in coronary artery disease. Circulation 1980; 62: Suppl III, 87. Hecht HS, Hopkins JM: Exercise-induced regional wall motion abnormalities on radionuclide angiography are not specific for coronary artery disease. Circulation 1980; 62: Suppl III 147. Josephson MA, Hecht HS, Hopkins JM, Singh BN: Oral verapamil vs. propranolol in coronary artery disease: Evaluation of left ventricular function by exercise radionuclide ventriculography. American Journal of Cardiology 1981; 47: 463. Ormiston JA, Shah PM, Tei C, Hecht HS: Abnormal mitral annular contraction in cardiomyopathies and correlation with left ventricular function. American Journal of Cardiology 1981; 47: 4091. Chew CYC, Hecht HS, Schnugg SJ, Hopkins JM, Singh BN: Differing effects of verapamil relative to varying levels of myocardial performance in patients with coronary artery disease. American Journal of Cardiology 1981; 47: 406. Hecht HS, Josephson MA, Hopkins JM, Singh BN: Reproducibility of exercise radionuclide angiography in coronary artery disease. Journal of Nuclear Medicine 1981; 22: 17. Hecht HS, Ormiston JA, Schnugg SJ, Karahalios S, Hopkins JM, Singh BN: Radionuclide and hemodynamic evaluation of acute effect of oral Iskrdil on exercise performance in congestive heart failure. Journal of Nuclear Medicine 1981; 22: 47. Nademance K, Hendrickson J, Peterson B, Cannom D, Hecht HS, Singh BN: Amiodarone: Possibly an ideal antiarrhythmic agent. American Journal of Cardiology 1982; 49: 1981.
2.0 Approval of the Agenda 3.0 EDCTP procedures 4.0 Science and products 4.1 Scientific overview of the field 4.2 Products in the pipeline: Global TB Alliance 4.3 Products in the pipeline: International Union 4.4 Global funding needs of TB drug trials Coffee break 5.0 Discussion on products and science 6.0 Sites in Africa 6.1 Needs in field of TB treatment 6.2 Inter TB network 6.3 TB Iris network Lunch 7.0 Discussion on sites 8.0 Member States commitment 9.0 Concluding remarks 10.0 Recommendations on how to proceed in terms of products, sites and funding procedure 11.0 Summary of recommendation Tea!
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