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Since the contingent conversion price of $51.50 applicable to its $360 million of convertible debentures due 2021 and its $450 million of convertible debentures due 2022 was exceeded during the first twenty trading days of July 2003, as of the third quarter Teva will include these convertible debentures in its fully diluted EPS calculation. For purposes of calculating third quarter EPS, Teva's weighted average number of outstanding shares will increase by 19 million shares with a corresponding add back of their related financing expenses to net income. The debentures will remain convertible in future periods subject to Teva's share price exceeding $51.50 for twenty trading days within the first thirty trading days of each quarter. Shareholders' equity exceeded $2.2 billion at June 30, 2003, reflecting an increase of $376 million over the level at December 31, 2002, comprising mainly the net income generated in the first six months of 2003, including one time items and positive translation differences, especially as a result of the strengthening of currencies against the US Dollar, less the dividend distributed through June 30, 2003. Teva's principal sources of short-term liquidity are its existing cash and internally generated funds, which Teva believes are sufficient to meet its operating needs and anticipated capital expenditures over the near term. Teva's cash is invested in high rated liquid short and long-term corporate bonds that bear fixed and floating interest rates. Teva continues to review additional opportunities to acquire companies in the generic pharmaceuticals industry and to acquire complementary technologies or product rights. To the extent that any such acquisitions involve cash payments rather than the issuance of shares, they may require Teva to draw upon its credit lines available from Israeli and other banks, or may involve raising additional funds from debt or equity markets. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK Reference is made to the "Quantitative and Qualitative Disclosures About Market Risk" section Item 11 ; in Teva's Annual Report on Form 20-F for the year ended December 31, 2002. LEGAL PROCEEDINGS Reference is made to the "Legal Proceedings" section in Teva's Annual Report on Form 20-F for the year ended December 31, 2002, as updated under the "Legal Proceedings" section on Teva's Report on Form 6-K relating to the quarter ended March 31, 2003. Except as described below, there were no material developments to such legal proceedings during the quarter ended June 30, 2003 and nimotop.
The following are commonly asked questions about providing adolescents with reproductive health information and services. Although questions can be seen as criticism, they actually provide opportunities to educate opinion leaders and the public. Answering questions accurately and honestly shows that advocates are professional and serious about the issues. Before beginning an advocacy campaign, advocates should anticipate questions and criticisms and plan their responses. Shouldn't family members and elders be the ones responsible for teaching children about sexuality? Young people often say they want to be able to talk with their parents about their reproductive health, and communication between parents and children is very important. Unfortunately, many adults do not know what to say or how or when to say it, and feel uncomfortable talking with young people about sexuality. As societies change, few families have the opportunity to utilize traditional sexuality education. A family's silence can give its young people the message that sexuality is bad and should not be discussed. With no other clear source of knowledge and values, young people often look to the popular media and their peers for information.
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Pharmaceutical Affairs Law which will increase efficiency and competition in the industry. New measures include the easing of previous restrictions on outsourcing production of intermediates to third parties. The outsourcing-related aspects take effect in 2003 but drug companies are already responding to the new flexibility. Takeda is to increase outsourcing of drug production from 30% to 70% by 2006. However, Takeda will continue in-house production of bulk actives. The immediate impact of the new law will be on older, generic drugs. The outsourcing rate in the Japanese drugs industry is expected to be 20-25%, compared with 30-40% for the European industry and 50-60% in the US. May 20, 2002 ; US-based Ricerca and Sumika Fine Chemicals of Japan have established a strategic partnership to develop and market Active Pharmaceuticals Ingredients APIs ; . The partnership will also promote chemical process development and scale up commercial manufacturing capacity to biotechnology and pharmaceutical companies. Under the partnership, which is renewable after the first three-year term, Ricerca will render process chemistry, development, scale-up and API production services through Phase II of the clinical development program for its clients' project. Sumika will take over the Phase III clinical trials and commercial API manufacture. The partnership enables Ricerca to offer development capabilities to its clients, which have the opportunity to utilize Sumika's three world-class facilities in Japan as well as production sites in Europe and the US. May 13, 2002 and nicotine.
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32. In the treatment of a patient, where proven prophylactic, diagnostic and therapeutic methods do not exist or have been ineffective, the physician, with informed consent from the patient, must be free to use unproven or new prophylactic, diagnostic and therapeutic measures, if in the physician's judgement it offers hope of saving life, re-establishing health or alleviating suffering. Where possible, these measures should be made the object of research, designed to evaluate their safety and efficacy. In all cases, new information should be recorded and, where appropriate, published. The other relevant guidelines of this Declaration should be followed and orap.
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